Katherine Stitzel
LD50 Test. The traditional LD50 (lethal dose 50%) test forces animals to. it would be irresponsible [for companies] not to use these. [ alternative] tests.
Why modification of the LD50 test will not be enough
In a national collaborative study an alternative to the classical LD50 test--the acute-toxic-class method--was validated. With this testing procedure mortality ranges are.
A national validation study of the.
... needed for any of the alternatives are drastically reduced and would normally be well below one-third of those used for the conventional LD50 test. Moreover, one of the alternative.
Drop of 30 percent in use of animals in.
Titre du document / Document title A national validation study of the acute-toxic-class method : an alternative to the LD 50 test Auteur(s) / Author(s)
LD50 - Lethal Dose 50%
Titre du document / Document title Oral acute toxic class method : A successful alternative to the oral LD 5 0 test Auteur(s) / Author(s) SCHLEDE Eva; GENSCHOW Elke; SPIELMANN Horst.
Median lethal dose - Wikipedia, the free.
Alternative Methods for the Median Lethal Dose ( LD50) Test: The Up-and-Down Procedure for Acute Oral Toxicity
Alternative Approaches in Median.
Publication » Alternative approaches in median lethality ( LD50) and acute toxicity testing.
The international validation of a.
The LD50 test was introduced by Trevan in 1927 (1) for biological standardization of dangerous drugs. Since then, the LD50 has gained wide acceptance as a measure of acute toxicity.
AnimAlt-ZEBET
As an alternative to the traditional LD50 test stipulated in OECD guideline 401, the acute toxic class method (ATC method) is a stepwise protocol for testing the acute oral.
New England Anti-vivisection Society.
... the National Institute of Environmental Health Sciences said today in releasing two new federal interagency reports on alternative testing methods. The old LD50 test.
OECD Test Guideline 401 was deleted in.
The LD50 test and its variants are now considered obsolete. Internationally accepted alternative tests, using fewer animals and "absence of evident toxicity", rather than death, as.
Review of revised UDP test methods with three levels of testing.
alternative test methods to the "Mouse LD50 Assay for Botulinum Toxin Potency Testing" be. potential of alternative methods to substitute for the mouse LD50 test by stating that.
Nomination to ICCVAM: Alternative Methods to Replace the Mouse.
In a recent monograph on BoNT type A (European Pharmacopeia (EP) , 2005) , the EP noted the potential of alternative methods to substitute for the mouse LD50 test by stating that.
ICCVAM Test Method Recommendations for the UDP - Appendix A of.
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for.
Alternative Methods for the Median Lethal.
The international validation of a fixed-dose procedure as an alternative to the classical LD50 test.
|
|